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Introducing the cryoWriter:

a groundbreaking solution developed from our extensive experience in cryo-EM. This innovative tool addresses both our insights and feedback we've gathered from our partners in the academic and industrial sectors. With the cryoWriter, we aim to enhance research capabilities and meet the evolving demands of the cryo-EM community. Join us in advancing the future of cryo-EM research.

cryoWriter at a glance

  • fully automated workflow with grid loading, glow discharging, grid writing, vitrification, grid storage

  • lowest required sample volume in the market (few nL)

  • unique protein concentration feature through the MagTrap

  • unique built-in protein isolation through the MagTrap

  • Multi-Sample-/Multi-Layer-Writing

  • proprietary cryoWriter OS with very broad setting options

  • ... 

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  • Swiss Made

Grid loading

the cryoWriter gripper uses computer vision control to select pre-loaded grids in the grid loader, takes the grid to the vacuum plasma glow discharger for hydrophilisation and places it on the launchpad for writing

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Pipette Unit

The pipette unit is a central element of the cryowriter. With its capillary pipette and precise pump unit it is able to aspirate and dispense samples and other fluids in nanoliter precision, to perform protein isolation when placed in the MagTrap, and to write a grid.

A dedicated and temperature controlled sample incubator allows for different samples, buffer solutions and other fluids.

The launchpad

The temperature controlled launchpad  I the place where the grid writing takes place.

 

The capillary pipette allows for settings of different writing forms and speeds (micrometer precision), with different writing volumes, and the writing process is permanently camera-controlled.

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Dimensions:WxLxH 

Ethane safety:

cryoWrite OS:

 

Site requirements

Set-up site:

Power:

Operating space:WxLxH

Weight:

Pressurized air:

Air exhaust:

Technical Data

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92×114×158 cm

Hood connected to an explosion-protected exhaust

ROS2-based, python script extensible (windows 10)

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Indoors only, 15-30 ℃, RH <70%

110 to 250 V AC - 2.5 kW - 40 to 60 Hz

220×260×200 cm

ca. 450 kg

≥6 bar

Exhaust pipe compliant with possible exit of process gases and substances (e.g. ethane)

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